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The mechanism by which NMU induces mutations is primarily through its alkylating properties. Upon exposure, NMU can add alkyl groups to DNA bases, leading to mispairing during DNA replication. This results in transitions or transversions in the nucleotide sequence, which can ultimately lead to permanent mutations. If these mutations occur in critical genes responsible for regulating cell growth and division, such as proto-oncogenes and tumor suppressor genes, they may lead to uncontrolled cell proliferation and cancer.
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Moreover, PQQ is renowned for its potent antioxidant properties. Oxidative stress, which is an imbalance between free radicals and antioxidants in the body, is a major contributor to the development of numerous chronic conditions, including cardiovascular diseases, neurodegenerative disorders, and even cancer. PQQ helps neutralize free radicals, thereby reducing oxidative damage to cells and tissues. This protective effect may assist in mitigating the aging process and promoting healthier aging.
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