E516 is a blend of calcium sulfate and sodium sulfate, both of which occur naturally. Calcium sulfate, often found in gypsum, has been used for centuries in various applications, including construction and food production. Sodium sulfate, on the other hand, is utilized in a wide range of industrial applications, including the manufacture of glass, textiles, and detergents. In the food industry, E516 is primarily employed to enhance the texture and stability of food products.