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When considering the incorporation of Pen-Strep into cell culture media, it is important to understand its concentration and effects on cells. Typically, the standard concentration of Pen-Strep used is 100 U/mL of penicillin and 100 µg/mL of streptomycin. This concentration is deemed effective for preventing bacterial growth without significantly impacting the growth and function of most mammalian cells. However, researchers must be cautious about long-term exposure, as prolonged use can lead to altered cell behavior, antibiotic resistance, and changes in metabolic activity.
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In addition to its effectiveness against gastrointestinal worms, albendazole is critical in the treatment of more severe infections. Neurocysticercosis, caused by the larval cysts of the pork tapeworm Taenia solium, can lead to serious neurological complications. In such cases, albendazole is often administered alongside corticosteroids to mitigate inflammatory reactions as the cysts die off. Similarly, it is employed in the management of echinococcosis, a serious condition caused by Echinococcus granulosus, which can form cysts in vital organs.
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