

The supply chain for APIs is intricate, often spanning multiple countries and industries. The globalization of API manufacturing has benefits, including cost reduction and access to a broader range of expertise. However, it also presents challenges, such as ensuring a consistent supply of high-quality materials. The COVID-19 pandemic underscored these vulnerabilities, highlighting the importance of supply chain resilience in the pharmaceutical sector.
Amino acids are the building blocks of proteins, and their derivatives play a pivotal role in metabolic pathways. d,l-α-Ketoisoleucine is particularly relevant in the context of branched-chain amino acids (BCAAs), which are essential for muscle protein synthesis and energy production. The presence of the keto group in its structure allows it to participate in the transamination process, where it can be converted into other amino acids or energy substrates, particularly during periods of fasting or intense exercise.