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Molecular weight also plays a pivotal role in determining HPMC's solubility. Lower molecular weight HPMC is generally more soluble in organic solvents than its high molecular weight counterparts due to the reduced entanglement of polymer chains. This characteristic can be particularly important during the processing of drug formulations, where the solubility and viscosity of HPMC can significantly impact the release profile of the active pharmaceutical ingredient (API).
hpmc solubility in organic solvents

The food industry also benefits from hydroxyalkyl cellulose, where it functions as a food additive. It acts as a thickener, stabilizer, and emulsifier, improving the texture and mouthfeel of various food products. HAC is commonly used in bakery products, sauces, and dairy products, contributing to enhanced quality and shelf-life. Moreover, as consumer demand for clean-label products rises, the use of hydroxyalkyl cellulose, which is considered a safe and non-toxic ingredient, aligns well with market trends focused on natural and health-conscious choices.