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In addition to the 35% and 47% oil seals, there is also the 7% oil seal, which is designed for smaller applications where space is limited. Despite its compact size, the 7% oil seal offers reliable sealing performance and is commonly used in small engines, pumps, and compressors.
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In addition to the 35% and 47% oil seals, there is also the 7% oil seal, which is designed for smaller applications where space is limited</strong></a>. Despite its compact size, the 7% oil seal offers reliable sealing performance and is commonly used in small engines, pumps, and compressors.
2025-08-14 14:52
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    In the pharmaceutical industry, HPMC Ltd’s products are often used as a binder in tablet formulations
    hpmc
    hpmc ltd. HPMC can improve the hardness, disintegration, and drug release of tablets, making it a valuable ingredient for pharmaceutical manufacturers. It is also used in ophthalmic preparations, topical creams, and suspensions due to its thickening and stabilizing properties.
    In the pharmaceutical industry, HEC is used as a binder in tablets and as a thickening agent in oral suspensions. The concentration of HEC in these formulations is carefully controlled to ensure proper viscosity for ease of administration and optimal drug delivery
    hydroxyethyl
    hydroxyethyl cellulose viscosity concentration.

    For hydroxypropyl cellulose (E 463), the identified NOAEL corresponded to the highest dose 6,000 mg hydroxypropyl cellulose/kg bw per day (by gavage). The most relevant feeding studies with HPMC (E 464) were performed in rats which tolerated up to 10%, corresponding to 9,000 mg test item/kg bw per day. Rabbits tolerated up to 7,500 mg HPMC/kg bw per day administered via the diet (30 day exposure) and dogs up to 1,500 mg HPMC/kg bw per day, in either case being the highest tested dosages. More studies were conducted using sodium carboxy methylcellulose (E 466). The most relevant ones were conducted in rats, with NOAEL values ranging from 4,500 to 9,000 mg test item/kg bw per day (in all cases the highest dose tested). In these studies, some effects (caecum and colonic enlargement, urothelial hyperplasia, nephrocalcinosis, diffuse epithelial hyperplasia in the urinary bladder) were observed, however, not considered of toxicological concern: the findings in the gastrointestinal tract were considered to be a consequence of the accumulation of poorly absorbed water-soluble material and the findings in kidneys and urinary bladder were attributed to the up to fourfold higher concentration of sodium in the test diet compared with the basal diet. In one further study, rats were daily exposed (gavage) to doses equivalent to 0, 500, 2,500 or 5,000 mg/kg bw per day. Animals treated with ≥ 2,500 mg/kg bw per day had soft and pale faeces, which was attributed to the presence of test material and not considered of toxicological relevance. In the absence of any other adverse effects, also for this study, the identified NOAEL was the top dose (5,000 mg/kg bw per day).