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The glass transition temperature for HPMC varies based on its molecular weight and substitution level. Generally, lower molecular weight grades of HPMC exhibit lower Tg values compared to their high molecular weight counterparts. This variance arises because lower molecular weight materials possess fewer entanglements among polymer chains, leading to enhanced molecular mobility at lower temperatures. As a result, the Tg of HPMC can range from approximately 50°C to 120°C. Understanding this range enables manufacturers to select the appropriate grade of HPMC for specific applications, ensuring the material performs effectively under operational conditions.
hpmc glass transition temperature

2. Controlled Release HPMC is often used in formulating controlled-release supplements. By adjusting the viscosity of HPMC, manufacturers can create time-released formulations that allow active ingredients to be released into the body gradually. This is particularly beneficial for ensuring optimal absorption of nutrients over an extended period, rather than a sudden influx.
hydroxypropyl methyl cellulose in supplements
