

One of the remarkable features of HPMC is its amphiphilic nature, which means it has both hydrophilic (water-attracting) and hydrophobic (water-repelling) regions within its structure. This property is pivotal, as it allows HPMC to interact well with both water and organic solvents. The balance between hydrophilic and hydrophobic interactions can be tailored by adjusting the ratios of hydroxypropyl and methoxy groups during the preparation process, enabling formulators to develop products with specific characteristics.