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Research suggests that anesthesia, including sevoflurane, may disrupt the normal sleep architecture. Sleep is typically characterized by distinct stages, including REM (rapid eye movement) and non-REM sleep. Anesthesia may alter the balance between these stages, potentially impacting the overall quality of sleep. Therefore, while sevoflurane induces a sleep-like state, it does not necessarily contribute to the same benefits as natural sleep.
Moreover, PQQ exhibits neuroprotective properties, which are particularly beneficial for brain health. Studies have indicated that the compound may help in the prevention of neurodegenerative diseases by supporting mitochondrial function and reducing oxidative damage in neuronal cells. This effect is critical since neurons are highly dependent on energy and are particularly vulnerable to mitochondrial dysfunction.